Computer-aided liver tumor segmentation can effectively reduce the workload of doctors and improve the success rate of surgery, and it has important clinical diagnosis and treatment value. Meanwhile, recently proposed U-Net model has achieved great success in the field of medical image segmentation. To obtain more accurate liver tumor segmentation results, this paper proposed an improved U-net model, i.e., cascaded separable and dilated residual U-Net (CSDResU-Net), for this medical application. CSDResU-Net utilizes cascade operation to solve the problem of unbalanced data in tumor segmentation due to the small proportion of tumors in the whole image. Besides, residual unit, depthwise separable convolution and dilated convolution are integrated into a single network to increase the convolution kernel receptive field, which can quickly extract more discriminative liver image features and lead to the performance improvement of liver tumor segmentation. Experimental results on the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) liver tumor segmentation (LiTS) benchmark dataset show that CSDResU-Net is relative to the baseline. The method improves the performance of the Dice coefficient by 1.3%, and at the same time proves that different void ratios have a greater impact on the performance of the segmentation network.
YU Qun, ZHANG Jianxin, WEI Xiaopeng, ZHANG Qiang
. Cascaded Separable and Dilated Residual U-Net for Liver Tumor Segmentation[J]. Journal of Applied Sciences, 2021
, 39(3)
: 378
-377
.
DOI: 10.3969/j.issn.0255-8297.2021.03.004
[1] Mcglynn K A, London W T. The global epidemiology of hepatocellular carcinoma: present and future[J]. Clinics in Liver Disease, 2011, 15(2): 223-243.
[2] 乐美琰, 魏千越, 邓炜, 等. 基于电子计算机断层扫描图像的肝癌病灶自动分割方法研究进展[J]. 生物医学工程学杂志, 2018, 35(3): 481-487, 492.Le M Y, Wei Q Y, Deng W, et al. A review of automatic liver tumor segmentation based on computed tomography[J]. Journal of Biomedical Engineering, 2018, 35(3): 481-487, 492. (in Chinese)
[3] Krizhevsky A, Sutskever I, Hinton G E. ImageNet classification with deep convolutional neural networks[C]//Proceedings of the International Conference on Neural Information Processing Systems, Lake Tahoe, USA, 2012: 1097-1105.
[4] Ke H, Dan C, Li X, et al. Towards brain big data classification: epileptic EEG identification with a lightweight VGGNet on global MIC[J]. IEEE Access, 2018, 6: 14722-14733.
[5] He K M, Zhang X, Ren S Q, et al. Deep residual learning for image recognition[C]//Proceedings of the 29th IEEE Conference on Computer Vision and Pattern Recognition, Las Vegas, USA, 2016: 770-778.
[6] Shelhamer E, Long J, Darrell T. Fully convolutional networks for semantic segmentation[C]//Proceedings of the 28th IEEE Conference on Computer Vision and Pattern Recognition, Boston, USA, 2015: 3431-3440.
[7] Ronneberger O, Fischer P, Brox T. U-Net: convolutional networks for biomedical image segmentation[C]//Proceedings of the 18th International Conference on Medical Image Computing and Computer Assisted Intervention, Munich, Germany, 2015: 234-241.
[8] Christ P F, Elshaer M E A, Ettlinger F, et al. Automatic liver and lesion segmentation in CT using cascaded fully convolutional neural networks and 3D conditional random fields[C]//Proceedings of the 19th International Conference on Medical Image Computing and Computer Assisted Intervention, Athens, Greece, 2016: 415-423.
[9] 徐宝泉, 凌彤辉. 基于三维全卷积网络的肝脏和肝癌分割算法研究[J]. 计算机测量与控制, 2019, 27(9): 199-203, 208. Xu B Q, Ling T H. Research on liver and liver tumor segmentation algorithm based on 3D fully convolutional network[J]. Computer Measurement and Control, 2019, 27(9): 199-203, 208. (in Chinese)
[10] Li X M, Chen H, Qi X J, et al. H-DenseUNet: hybrid densely connected UNet for liver and tumor segmentation from CT volumes[J]. IEEE Transactions on Medical Imaging, 2018, 37(12): 2663-2674.
[11] Zhang J P, Xie Y T, Zhang P P, et al. Light-weight hybrid convolutional network for liver tumor segmentation[C]//Proceedings of the International Joint Conference on Artificial Intelligence, Macao, China, 2019: 15-21.
[12] Patrick B, Patrick F C, Eugene V, et al. The liver tumor segmentation benchmark (LiTS)[DB/OL]. Computer Vision and Pattern Recognition, 2019[2020-08-26]. https://arxiv.org/abs/1901.04056.
[13] Kaluva K C, Khened M, Kori A, et al. 2D-densely connected convolution neural networks for automatic liver and tumor segmentation[J/OL]. arXiv: Computer Vision and Pattern Recognition, 2018[2020-08-26]. 1802.02182v1.
[14] Xi X F, Wang L, Sheng V S, et al. Cascade U-ResNets for simultaneous liver and lesion segmentation[J]. IEEE Access, 2020, 8: 68944-68952.