Abstract: The inclusion complex of caffeine and β-cyclodextrin was prepared, and its properties were studied by using the thermogravimetry-differential thermal analysis, nuclear magnetic resonance and infrared spectroscopy. The experi mental results showed that the caffeine molecule was included in the hydrophobic cavity of β-cyclodextrin molecule and its thermal stability was increased.

Key words: Caffeine, β-Oyclodextrin, Inclusion complex, TG-DTA (Thermogravimetry-differential thermal analysis)